Test, don't guess. A blood test costs less than a month of pills you might not need.
Something I've been reading into, and it turned into more than a note: the vegetables and fruit we buy today carry less of some minerals and vitamins than the same crops 50 to 80 years ago — the studies put it between roughly 6 and 38 percent depending on the nutrient. That matters more for women than for most people, because iron, magnesium, B6 and vitamin D all move with the cycle. So here is the long version: what the studies actually show, where women stand today, what a period costs in iron, and what to do about it. Every number has a source at the bottom.
A note on how this came about: a friend pointed me to the nutrition score printed on many German products, A to E. We stood in the shop and most of what we picked up was a D or an E. The first A we found was a mix of nuts and seeds that looked like bird food. Since then I read that little label, and I read the studies below. Otherwise we just get full, fat and tired, when we could eat less and feel energised because the body got what it needs.
the most cited study compared US nutrition tables for 43 garden crops, 1950 versus 19991. six of thirteen nutrients showed a reliable drop in the median: protein −6 %, phosphorus −9 %, iron −15 %, vitamin C −15 %, calcium −16 %, riboflavin (B2) −38 %. the other seven did not change reliably. a UK comparison of 1940 versus 2019 found iron −50 %, copper −49 % and magnesium −10 % across 20 vegetables and 20 fruits2,3.
only 6 of 13 nutrients showed a reliable change; 7 did not. source: Davis, Epp & Riordan, J Am Coll Nutr 2004.
the honest caveat. a 2017 review4 warns that comparing tables decades apart is shaky: varieties, origin, ripeness and lab methods all changed. the "30 % less" headline you may have seen is a simplification. what holds up: some nutrients in some crops are lower, most plausibly because of high-yield varieties (the "dilution effect"), and this is best documented in wheat. the variety you buy and how fresh it is matter more than the decade.
the food tables are the small story. the big one is what is measured in women's blood and diets today5–10:
sources: WHO / World Bank 2023 · Blood 2025 meta-analysis of 71 studies (270,907 women) · RKI DEGS1 (6,995 adults) · Nationale Verzehrsstudie II.
every period costs iron. about 0.4–0.5 mg per millilitre of blood; the median bleed is 20–30 ml, so roughly 10–15 mg per cycle14–16. with heavy periods (over 80 ml, fewer than 1 in 10 women) it is 32–40 mg. that is why heavy bleeding is a named risk group for iron deficiency, and why a ferritin test is the first thing gynaecologists recommend when bleeding is heavy14,15.
reference intake for women 19–50: 16 mg iron per day from food (DGE 2024). the body absorbs only a fraction, which is why the daily number is higher than the monthly loss.
and the supplements everyone talks about for PMS and cramps? here is what the trials actually show, sorted by how solid the evidence is:
| nutrient | what was found | evidence |
|---|---|---|
| iron | measured deficiency is common and the fix is well established: eat iron-rich food, test ferritin if periods are heavy or you are often tired7,14,15 | strong |
| calcium | 1,200 mg/day for 3 cycles cut PMS symptom scores by 48 % vs 30 % on placebo in 466 women. one large trial, 199822 | moderate |
| vitamin B6 | 9 trials, 940 women: about twice the odds of PMS improvement. but the trials were of mixed quality, and the EU safety limit is now 12 mg/day because of nerve damage at high doses20,21 | moderate, dose caution |
| omega-3 | 8 small studies: clearly less period pain at 300–1,800 mg/day over 2–3 months. promising, not proven26,27 | moderate |
| magnesium | "promising" for cramps in 2001, "no high-quality evidence" in the 2016 update; for PMS "insufficient evidence" in 202417–19 | weak / mixed |
| vitamin D | less period pain in two meta-analyses, but mostly high-dose trials that disagree with each other; PMS: inconclusive23–25 | weak / mixed |
| "detox" | no trial base at all. megadoses have documented harm: B6 above 12 mg, iron above 40 mg, supplemental magnesium above 250 mg21,28,29 | none |
food first. these are the german reference values for women 19–50 and where the nutrients sit30–35:
| nutrient | per day | best from |
|---|---|---|
| iron | 16 mg (11 mg if you don't menstruate) | lentils, beans, oats, pumpkin seeds, red meat. add vitamin C (peppers, citrus), keep coffee and tea an hour away |
| magnesium | 300 mg | whole grains, nuts, seeds, legumes, dark greens |
| vitamin D | 20 µg when there is no sun | oily fish, eggs; sun on skin april–september |
| folate | 300 µg (+400 µg folic acid if pregnancy is possible) | greens, legumes, whole grain |
| iodine | 150 µg | iodised salt, sea fish, dairy |
| B12 | 4 µg | animal foods; vegans: supplement, no way around it |
test, don't guess. ferritin (plus CRP) if your periods are heavy, tiredness won't go, or you eat mostly plants. 25(OH)-vitamin D in winter. B12 if you are vegan. then supplement only the measured gap, within the safety limits, with your doctor. a blood test costs less than a month of pills you might not need.
this is general information, not medical advice. if something feels off, talk to your doctor.
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